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doi:10.3945/ajcn.110.004945 Rizza S, Muniyappa R, Iantorno M, et al

Before binding to specific DNA locus antioxidant response elements (AREs), Nrf2 will heterodimerize with Maf or Jun proteins in the nucleus (259, 260)

The metabolic pathways and corresponding enzymes are organized around the TCA cycle at the center, branching out to include amino acid metabolism, purine metabolism, and the glutathione cycle, highlighting the interconnectivity and complex response to the oxidative stress induced by the absence of GR

Over time, she gained back her energy and was even able to get pregnant and have a child on her own, something she had given up on entirely

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