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PMID: 41542313

10.1177/20503121231209088 218 YangH.LiuC.YuanF.LiF

The cells were cultivated for seven days, during which the formation of the epithelial barrier was established

When the complemented mutant cells were grown in different stress conditions, GLYI complemented cells showed more tolerance followed by D-LDH complemented cells and the GLYII complemented cells (Fig

This hypothesis was grounded in the observations that alcohol-elicited place conditioning is prevented by DA receptor antagonists [15, 16], that caffeine exerts, through an antagonistic action on A 2A adenosine receptors (A 2A R) [17], a direct negative control on neuronal firing of DA cells in the posterior ventral tegmental area (pVTA) [18], and that caffeine administration prior to alcohol also prevents its DA-dependent [19] ability to increase the expression of phosphorylated Extracellular signal Regulated Kinase (pERK) in the shell of the nucleus accumbens (AcbSh) [13, 20]