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Abstract Therapy resistance is attributed to over 80% of cancer deaths per year, emphasizing the urgent need to overcome this challenge for improved patient outcomes

injections are painful, whilst for those with poor compliance with oral intake, injections may be preferable

It is applied directly to the skin, where it can penetrate the dermal layers and exert its regenerative effects

Age plays a modest role, with older adults sometimes experiencing slightly slower clearance, though age alone is not a strong determinant

The velocity and severity of the degenerative process most likely depends on the function of the opposite endplate