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However, the reproductive toxicity of Tripterygium wilfordii limits its clinical application, and its mechanism of reproductive toxicity is not fully understood [118]

RLRs are a group of three intracellular innate immune receptors: RIG-I (retinoic acid-inducible gene I) like receptor, MDA5 (melanoma differentiation-associated protein 5), and LGP2 (laboratory of genetics and physiology 2)