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Sevak P, Pushkar B

What Happens After the July 2026 Meeting

Side Effects and Safety# Epitalon Safety Profile# Preclinical record: No significant adverse effects across decades of animal studies Injection site effects: Mild redness and transient discomfort at injection sites Cancer concern: Telomerase activation theoretically risks promoting pre-cancerous cells, though Epitalon studies showed reduced rather than increased tumor incidence Limitation: Safety data predominantly from a single research group without large-scale, independent safety assessments NAD+ Safety Profile# Human trial data: NMN (250-1200 mg/day) and NR (300-2000 mg/day) have shown favorable safety in multiple human studies lasting weeks to months Common effects: Mild GI symptoms (nausea, bloating) at higher doses

Abnormal gene expression in uterine leiomyomas

This function is closely linked to their ability to induce mitochondrial oxidative stress and activate hypoxic responses/HIF1a (139)