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Remarkably, all 12 patients reported significant improvement in symptoms and none reported adverse effects in the short term

Lancet 403 , 984996 (2024)

And so learning the cell danger response, I think, has become a very therapeutically, almost essential, We fortunately have some labs now, that can show us some of this before it was just in the research phase

We also studied the consequences of PA treatment on the expression of other well-known ferroptosis-related genes and found that PA induced a decreased expression of two key anti-ferroptotic genes: the gluthatione peroxidase 4 (GPX4) and the ferroptosis suppressor protein 1 (FSP1) and an enhanced expression of two key pro-ferroptotic genes: the arachidonate 15-lipoxygenase (ALOX15) and the acyl-CoA synthetase long chain family member 4 (ACSL4)