glutathione isothiocyanate Evolution of the active site of human transferase A2-2 for enhanced activity with dietary isothiocyanates Frontiers | The role of

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A randomized double-blind placebo-controlled phase IIB trial treated patients with oral leukoplakia using curcumin (3.6 g daily for 6 months) and noted a significant and durable clinical response, including reduction in lesion size and histopathological improvement in terms of reduced dysplasia in some cases (Kuriakose et al., 2016)

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Johnston C, et al