antioxidant glutathione synthesis protein The “Glutathione Pathway.” Glutathione synthesis,

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Increased G6PD activity, which is the gatekeeping enzyme of the pentose phosphate pathway [69], and xanthine suggest an increased turnover rate for purine nucleosides, which may arise from the increased DNA damage from continuous exposure to tamoxifen

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Increased expression of GPX3 has been associated with unfavorable patient prognosis in OC, stem cells and certain colorectal cancers (44,52)

The supernatant was then aspirated, and the cells were flash frozen or immediately lysed in 450 uL of ice cold 1X Denaturing Lysis buffer (1X RIPA, supplemented with 1X protease inhibitor, 1X phosphatase inhibitor, 50 mM N-Ethylmalamide, and 5% 2-mercaptoethanol) and boiled at 95 C for 5 min