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Additionally, pharmacological Nrf2 activation worsens diabetic nephropathy in rats [78]

Gorrini C, Baniasadi PS, Harris IS, Silvester J, Inoue S, Snow B, et al

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In comparison, LUT-EX@MN treatment led to 1.16-, 1.21-, 1.28-, and 1.32-fold changes in the expression of these same genes relative to the negative control group