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These observations highlight the presence of metabolic modifications within the MM niche that may facilitate immune evasion strategies ( The high level of ADO detected in the BM niche may contribute to the overall anergic state observed in MM patients

I think its important to serve well where you are by becoming fully aware of the needs in your current environment and any future environments where you may have influence.

Mastrangelo et al., 2023)

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In the future, long-term clinical outcome studies should be strengthened, and exercise prescriptions should be refined based on CKD staging and comorbidities to achieve more precise interventions