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This glutathione depletion allows hydrogen peroxide to accumulate in thyroid cells, oxidizing thyroid proteins and creating neoantigens that the immune system attacks - amplifying the autoimmune response

At the same time, there is evidence of T cell exhaustion and reduced natural killer cell function, suggesting the immune system is simultaneously overactivated in some pathways and depleted in others

Order Online Now The symptoms and severity of symptoms vary between individuals but the main symptoms associated with vitamin B12 deficiency are extreme tiredness, lack of energy, breathlessness, feeling faint, palpitations, pale skin, loss of appetite and weight loss

doi: 10.1093/jn/136.3.588, 113

Zhong G, Chen F, Cheng Y, Tang C, Du J