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10.1073/pnas.1516953113 Proc

Monteiro-Soares M, Boyko EJ, Jeffcoate W, Mills JL, Russell D, Morbach S, et al

While the definitive diagnosis typically rests with the pediatric hepatologist, the onus of early suspicion and timely referral lies with the primary care provider

J Steroid Biochem Mol Biol 117:5666 Cavalieri EL, Devanesan P, Bosland MC, Badawi AF, Rogan EG (2002) Catechol estrogen metabolites and conjugates in different regions of the prostate of noble rats treated with 4-hydroxyestradiol: implications for estrogen-induced initiation of prostate cancer

The heavy subunit catalyzes formation of -glutamylcysteine, whereas the light subunit increases affinity for glutamate and decreases the inhibition by glutathione (Seelig et al., 1984