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AGS-30, an andrographolide derivative, suppresses tumor angiogenesis and growth in vitro and in vivo

293 In a mouse model of Barretts esophagus, feeding an HFD was observed to promote dysplasia and carcinogenesis by modulating the esophageal microenvironment and gut microbiome, thereby inducing inflammation and promoting stem cell proliferation

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The threshold for a significant vasorelaxation response to 10 M Ach was calculated as a decrease of more than 50% from the contraction following incubation with 0.5% plasma

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