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Notably, many non-histone lactylation modifications have been reported to play important roles, such as EGR1 and XRCC1 nuclear translocation, and LZKF1 transcriptional activity regulation 54,55

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In nerve samples from patients with Morton's neuroma, increased intraneural CD68 + macrophages have been positively correlated with burning pain, while higher expression of SR-A6 has been linked to paroxysmal pain, as measured by the Neuropathic Pain Symptom Inventory (196)

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