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The so-called GLP-1 patches contain some herbal ingredients that are claimed to have effects similar to these drugs, however, there is very limited scientific evidence to support these

Steven Yoelin as the Medical Director at The Skin Specialist Medical Aesthetics

PMC 4967041

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease

In particular, some research has linked vitamin B6 (pyridoxine), vitamin B9 (folic acid), and vitamin B12 (cobalamin) to an increased risk of lung cancer