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Challenges in Senomorphic Therapy Limited Clinical Evidence: While preclinical studies in animal models suggest that senomorphic compounds can effectively modulate the effects of senescence, clinical trials in humans are still relatively limited

When the environment improves, other remodeling signals become more effective

When used for less than two weeks, more rapid tapering of steroids is generally possible Infections Long-term steroids can suppress the protective role of your immune system and increase your risk of infection

[14] As a result, it has been described as over-prescribed for this application

It represents a monumental shift away from simply managing symptoms and toward fostering true biological repair