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2020;26(6):880895.e6

Hong L, Negrao MV, Dibaj SS, Chen R, Reuben A, Bohac JM, Liu X, Skoulidis F, Gay CM, Cascone T, Mitchell KG, Tran HT, Le X, Byers LA, Sepesi B, Altan M, Elamin YY, Fossella FV, Kurie JM, Lu C, Mott FE, Tsao AS, Rinsurongkawong W, Lewis J, Gibbons DL, Glisson BS, Blumenschein GR Jr, Roarty EB, Futreal PA, Wistuba II, Roth JA, Swisher SG , Papadimitrakopoulou VA, Heymach JV, Lee JJ, Simon GR, Zhang J

Considering the enzymatic activity of GLYR1 in converting glyoxylate to glycolate, it is expected that glyr1-1 hpr1-1 and glyr1-1 cat2-1 have lower levels of glycolate

however, the clinical effect was marginal and patient preference did not differ from placebo

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