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showed that low serum vitamin B12 concentrations were significantly associated with increased all-cause mortality ( Some cross-sectional investigations have found an inverse association between folate intake and the prevalence of NAFLD ( in vivo may be associated with a higher risk of mortality and studies from the general population have shown the benefits of folate intake, more direct clinical evidence is still needed as to whether folate supplementation can be used as a dietary intervention strategy for patients with MASLD

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The increase in the males could be explained by a higher concentration gradient for the buprenorphine to leave the SC tissues, resulting in a higher-than-predicted C max and AUC 0-t [18]