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ALA does not replace B12, and B12 does not replace ALA

The consensus among providers is to wait unless more safety data becomes available

Mechanisms by which PPIs, H2RAs, and metformin affect serum total vitamin B-12 concentrations PPIs and H2RAs are 2 classes of drugs that are used to treat conditions associated with excess gastric acid production, including dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, Barrett esophagus, and Zollinger-Ellison syndrome

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