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This random assignment ensured that half of the participants started the study with morning injections and the other half with evening injections.The schedules were standardized to 08:0009:00 and 20:0021:00, respectively, according to the patient's age

Clin Cancer Res 13(15 Pt 2)(15 Pt 2):s4583-4588, 2007

Therefore, inhibiting C5aR1 with an anti-C5aR1 antibody effectively suppressed the expressions of caspase-1 and IL-1, which implied that the C5a/C5aR1 signaling pathway was a potential target for SARS-CoV-2 treatment [30]