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It is a potent anti-oxidant that prevents oxidative stress induced by reactive oxygen species

J Immunol (2012) 188(1):218

It is worth noting that proinflammatory signaling favors proteolysis and amino acid catabolism (represented herein by increased acetyl-methionine and hydroxyproline and altered levels of free amino acids), which can be antagonized, in part, by antiinflammatory cytokines (e.g., IL-37) (54) or inflammasome inhibitors (55)

Recent advancements in mass spectrometry-based proteomics and structural biology have highlighted that -syn possesses a complex PTM landscape, where the interplay among distinct modification sites profoundly influences its structural stability and conformational transitions ( This review will specifically highlight the roles of PARP-1 in mediating in vivo nitration and phosphorylation of -syn, as well as structural and functional changes in -syn associated with PARP-1induced oxidative stress

The exact dosage is based on body weight