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AIDS 17(15):21592168 Arthur MJ, Lee A, Wright R (1984) Sex differences in the metabolism of ethanol and acetaldehyde in normal subjects

Preclinically, FMT from ICI-responding patients reprograms the gut microbiota of germ-free or ATB-treated mice not only by expanding beneficial taxa (e.g., Bacteroides thetaiotaomicron , Faecalibacterium prausnitzii ) but also by restoring critical metabolites: SCFAs (butyrate, acetate) that enhance CD8 + T cell infiltration into the TME and suppress Treg differentiation, and Trp derivatives (IPA) that activate the AhR to boost DC maturation (261, 290, 291)

Mechanism of Action: The FOXO4-p53 Axis In senescent cells, the transcription factor FOXO4 is upregulated and stabilized via the CHK2-USP37 axis, where the deubiquitinase USP37 prevents its proteasomal degradation (PNAS, 2026)

This work was supported by the Program of Science and Technology Department of Sichuan Province (grant nos

Strobilurin effects on nitrogen use efficiency for the yield and protein in durum wheat grown under rainfed mediterranean conditions