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This long-term effect was seen in the phase 2 trial of NRX-101 and the company is attempting to replicate this finding in a larger phase 3 trial

(8) A Steiger, J Guldner, U Hemmeter, B Rothe, et al (1992) Effects of growth hormone-releasing hormone and somatostatin on sleep EEG and nocturnal hormone secretion in male controls Neuroendocrinology, 1992 Oct, Volume 56 (Issue 4), Pages 566-73