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When MPNSTs arise in the head and neck, symptoms can include hoarseness , facial numbness , visual changes , or swallowing difficulties , depending on which cranial nerves are involved (Evans et al., 2021)

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Even a clean injection can cause swelling or a bad local reaction

On the other hand, patients with neurofibromatosis type 1 (NF-1) have a lifetime risk of developing an MPNST of 8-13%.3 The 2- and 5-year overall survival rates are 57% and 39%, respectively

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