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As a result, the transgene obtained an open chromatin structure compared to the normally nucleosome-flanked CGG repeats seen in other mouse models (Datta et al., 2011) and is therefore more prone to instability (cp

Uchiyama Y, Suzuki T, Mochizuki K, et al

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3) The mechanisms involved in the adaptive response against oxidative stress mediated by ROS-responsive transcription factors, involving up-regulation of GSH-synthesizing enzymes, GSH-detoxifying enzymes and the hepatocellular efflux pumps

GSH is in a class of molecules called antioxidants, whose primary job is to alleviate oxidative stress