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These verdicts indicated that hyperhomocysteinemia augments the inflammatory burden in PD patients through activation of the NF-B signaling pathway involved in the development and progression of PD

Additionally, those taking medications for heart disease, blood pressure, or neurological conditions should be especially cautious

Future studies on the role of oxidative stress in the comorbidity of both diseases should further clarify the nature of these processes, identify common mechanisms involved in the course of diseases, and consider the role of antioxidants in the development of therapeutic strategies

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