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Furthermore, methotrexate (MTX), the immunosuppressant commonly used for the treatment of RA, has been demonstrated that could reduce inflammation and subsequent tissue damage by inhibiting MAA-adducts formation and scavenging superoxide in RA [108]

SCD arises from an atypical HbS (2S2) where in the amino acid glutamic acid residue at position 6 in the -globin chain of haemoglobin is substituted with valine

Different (direct and indirect) mechanisms for the induction of DNAprotein crosslinks in human-cells by far-ultraviolet and near-ultraviolet radiations (290 and 405 Nm)

Nevertheless, allogenic cells, often utilized in regenerative therapies, have intrinsic limits and obstacles, including immunological reactivity, tumorigenic potentials, and ethical issues

doi: 10.1016/j.celrep.2016.10.074 108 KindeB.WuD