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Ceramides - lipotoxic inducers of metabolic disorders

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doi:10.2174/1381612828666220620160516 Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM

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It is postulated that AGEs participate in the pathological mechanism of cardiovascular disease, nephropathy, rheumatoid arthritis, dysfunctions in bone remodelling and neurological diseases (for example, Alzheimer's and Parkinson's disease), cancer growth, metastasis and other degenerative diseases (9,20-22)

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