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Growth hormone production peaks in adolescence and declines through adulthood, and IGF-1, the downstream messenger that drives muscle protein synthesis and tissue repair, declines along with it

Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID

This influx leads to a local inflammatory response by activating microglia and astrocytes, which produce pro-inflammatory cytokines and mediators such as TNF- and IL-1 [115, 116]