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NCT01357681)

PMID: 16245310

E.KayedR.et al

The reason for this inconsistency seems to be the results of differences in the amount of L-carnitine synthesized de novo in the body, which is influenced by the amount administered

Tumor-derived EV metabolites, such as succinate and glycolytic enzymes, influence metabolic reprogramming and the tumor microenvironment, but mechanistic data linking EV-mediated metabolic transfer to inflammation-driven colorectal carcinogenesis are still developing (Haque et al., 2025