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Many randomized, double-blind, placebo-controlled studies have shown that treatment with vitamin C consistently results in improved vasodilation in individuals with coronary heart disease, as well as those with angina pectoris, congestive heart failure, diabetes, high cholesterol, and high blood pressure (3, 94-96)

In the lipid-rich environment of the CNS, ferroptosis could therefore play a significant role in secondary damage, the neuron-astrocyte interaction is also critical for maintaining brain lipid metabolism, indicating that neurons may be more sensitive to drastic changes in lipid peroxidation, moreover, lipid peroxidation contributes to secondary damage after SCI and highlights the possible use of lipid metabolism regulator to treat SCI [46,47,48]

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10.1155/2021/7178253 172 SunM.ChangH.JiangF.ZhangW.YangQ.WangX.et al (2024)