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Furthermore, we also hypothesized there would be activation of kinase signal transduction pathways after PBMC recruitment to the lung or other organ and activation of specific canonical and signaling pathways that would govern disease progression or remission

La presencia de hiperbilirrubinemia indirecta con anemia y hepatoesplenomegalia sugiere hematopoyesis extramedular como causa de la hepatomegalia

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If folate deficiency is present, replacement should only be started after initiating B12 therapy to avoid worsening neurological symptoms