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10.1016/j.cell.2005.05.007 193

Other enzymatic sources of free radicals include myeloperoxidase (MPO), which normally catalyzes the H 2 O 2 -mediated oxidation of halide ions, but under pathophysiologic conditions oxidizes other substrates and mediates tissue damage [20]

These processes include the maintenance of ionic electrochemical gradients (Farsi et al., 2017), the regulation of ion channels (Becchetti et al., 2019), and the management of neurotransmitter release, uptake, and recycling (Armbruster et al., 2020

The assignment of every 1 H and 13 C resonance in the spectra establishes that no other species is present

Gene expression analysis For gene expression microarray analyses, GeneChip Human 1.1 ST arrays were hybridised according to Affymetrix recommendations, using the Ambion WT Expression Kit protocol (Life Technologies) and Affymetrix labelling and hybridisation kits, as previously described in ref