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In addition to direct testicular or oxidative mechanisms, there is an increasing recognition of several systemic and lifestyle-related factors as significant contributors to male infertility

Plant Physiol 133:748760 Navrot N, Collin V, Gualberto J, Gelhaye E, Hirasawa M, Rey P, Knaff DB, Issakidis E, Jacquot J-P, Rouhier N (2006) Plant glutathione peroxidases are functional peroxiredoxins distributed in several subcellular compartments and regulated during biotic and abiotic stresses

Since the mechanisms of action of vitamin C are becoming better defined, we can propose vitamin C combinations in a more rational, hypothesis-driven manner

Comprehensive and methodically designed investigations are necessary to address existing knowledge gaps in glutathione research

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