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Phase I Trial of UCN-01 in Combination with Topotecan in Patients with Advanced Solid Cancers: a Princess Margaret Hospital Phase II Consortium Study

showed that leukaemia inhibitory factor (LIF), a cytokine with pro-myelination ability, can be specifically delivered to oligodendrocyte precursor cells (OPC) to support their differentiation into mature oligodendrocytes which are capable of repairing myelin in-vivo [129]

The usual dose of 1 mg/kg/day for treating SLE exacerbations is empirical and is currently not recommended since it was observed that the resulting response rates after using high initial prednisone doses of 1 mg/kg/day did not differ significantly from those obtained for pulse methylprednisolone in lower doses (0.3 and 0.5 mg/kg day), whether CYC or MMF was used [40]

Similar to what was found for aesthetic value ratings, tests of simple main effects showed that older individuals found the real, AI, CGI, and enhanced categories significantly more sexually attractive than younger individuals (all t 2.70, r .11, adjusted p .014)