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PERK/EIF2AK3 integrates endoplasmic reticulum stress-induced apoptosis, oxidative stress and autophagy responses in immortalised retinal pigment epithelial cells

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Conclusion In conclusion, our observations support the concept that an HFD alters the output component of the circadian rhythm of the MGs, rather than the core clock machinery (Figure 7)

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Machine learning approaches, including random forests, support vector machines, and deep learning algorithms, have been successfully applied to multi-omics data for biomarker discovery and outcome prediction [74,75,76]