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Preclinical evaluations focus on how this combination might impact variables like IGF-1 concentrations, insulin sensitivity, and muscle-related anabolic signals

Prezioso JA, Hughey RP, Wang N, Damodaran KM, Bloomer WD

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Indeed, early presence of hypermethylated TSGs does not necessarily indicate an invasive cancer, as premalignant or cancer precursor lesions can also carry these epigenetic signatures