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Optimal amounts of L-glutathione are necessary for the proper function of the immune system, and to help the liver to detoxify chemicals

In RA pathogenesis, activated RA fibroblast-like synoviocytes (RA-FLSs) exhibit proliferative features similar to tumor cells and subsequently cause cartilage erosion, which will eventually lead to joint destruction (1, 2)

The effect of maternal embryonic leucine zipper kinase pharmacological inhibitors, which suppress ferroptosis in intestinal tissue and alleviate intestinal inflammation in mice with colitis, is closely related to the regulation of the gut microbiota [90]

However, supplementation with 437.85 mg/kg glutathione significantly reduced their mRNA and protein levels

Public Health 19 (23), 16322