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This leads to the cleavage and translocation of AIF from the mitochondrial intermembrane space to the nucleus, phosphorylation of the histone H2A family member H2AX, mitochondrial release of the death-inducing protein Smac/direct IAP-binding protein with low PI (DIABLO), and inhibition of the anti-apoptotic protein X-linked inhibitor of apoptosis (XIAP)

[Abstract] Ther Deliv

Science 379 , 523524 (2023)

J.ParksE

Interestingly, supplements that promote fat burning, like those in the Fat Burners category, often work synergistically with carnitine, as they both target the bodys ability to convert stored fat into usable energy