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This cascade restores PINK1/Parkin-dependent mitophagy and concurrently activates the NRF2 pathway, enhancing antioxidant responses, like NQO-1and HO-1, and consequently reducing oxidative stress in ectopic lesions

Mechanistically, GHK-Cu inhibited the expression of pro-inflammatory cytokines like IL-1$\beta$, IL-6, and TNF- alpha in colonic tissue

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