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GTPgammaS Science 1997

S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver

Designing the selenium and vitamin E cancer prevention trial (SELECT)

132 Zempleni, J., Galloway, J

This explains why also in aerobic conditions, glycolysis is heavily used by cells with a high anabolic need (i.e., a need of building blocks for the biosynthesis of nucleotides, lipids or proteins), even despite that such aerobic glycolysis (i.e., the conversion of glucose into pyruvate and subsequently lactate in the cytoplasm) is much less efficient in ATP generation compared to shuttling glucose-derived pyruvate to mitochondrial respiration (i.e., into the TCA/OXPHOS cycle)