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The sympathetic nervous system predominantly inhibits gastrointestinal muscle activity to maintain homeostasis, whereas the parasympathetic nervous system precisely regulates the rhythmic contraction and relaxation of the stomach and intestines [3]

Oliveira, N

Dosage: Adults and adolescents (18 years and older) should apply 2 grams (for hands, wrists, or elbows) or 4 grams (for feet, ankles, or knees) to the affected area four times daily, a sufficient amount to cover the treatment area