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The term oxidative stress, first introduced by Helmut Sies in the late 1980s ( In IBD, evidence suggests that oxidative stress plays a crucial role in the onset and progression of the disease ( Over the past decades, extensive research has been conducted to understand the mechanisms underlying oxidative stress in IBD

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Those at high risk of bleeding may benefit from more frequent INR monitoring, careful dose adjustment to desired INR, and a shortest duration of therapy appropriate for the clinical condition

Notably, deferred frozen-thawed embryo transfer (FET) may restore synchrony and reset the uterine environment, with studies reporting higher live birth rates and lower miscarriage rates compared to fresh transfer, though clinical routine use requires caution due to heterogeneity in evidence

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