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Briefly, bacterial pellets were lysed in buffer (150 mM NaCl 2 , 50 mM Tris, 10% (v/v) glycerol, 1 mM phenylmethylsulfonyl fluoride (PMSF) at pH 7.4 by bead-beating as described for the ATP assay

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Hamilton Depression Rating Scale (HDRS), 23 Beck Depression Inventory (BDI), 24 and Montgomerysberg Depression Rating Scale (MADRS) 25 as standardized mean differences (SMDs) and their corresponding 95% CI at end-of-treatment (negative values favor ALC) using random-effects (REML) models

Reitman adjusts the schedule based on follow-up blood work

Journal of Molecular Medicine , 95 (3), 323333