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Results Generation of a transcriptional signature and associated hub genes defining oligodendrogenesis We first set out to generate a broad transcriptional signature of oligodendrocyte lineage cells (Supplementary Data 1 and Supplementary Table 1) by comparing the transcriptome of these cells at different developmental stages, using recently published single-cell- and bulk-transcriptomic datasets from mouse brain cells 31,32,33,34,35,36