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Dania Abdelhady, [email protected]

CP proteins are capable of transporting intracellular proteins, lipids, and other accessory biomolecules to function in the organellar polarity distribution [90], which can be modulated by drug endocytosis and efflux

Ample of proteomics and metabolomics studies have proved the considerable lipid metabolism remodeling in the myocardium of AF patients ( 3 AR) ( 2+ -handling and cell contraction, mitochondrial biogenesis, cell growth and proliferation, and so on, thus exerting cardiovascular protection with a combination of multiple mechanisms ( via LCA, a natural and biologically active micronutrient enhancing physiological FAO through CPT1B (Figures 3, 6), can significantly reduce obesity-mediated AF propensity and the corresponding atrial remodeling (Figures 1, 2), thus better supports the efficiency of FAO promotion in the AF therapeutic approach

The expression of EAAT4 is thought to be limited to cerebellar GABAergic Purkinje cells, but it has also been observed in astrocytes (Wen-Hui et al., 2003)