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An international survey of patients with tetrahydrobiopterin deficiencies presenting with hyperphenylalaninaemia

MhTyrA was chosen as no TyrAs from its subclade of clade II have previously been characterized (Figure 2)

A 2008 follow-up in Inflammation Research characterized early functional recovery (days 14 post-transection) using the Achilles Functional Index, myeloperoxidase activity, and vascular index, and reported anti-inflammatory effects together with increased new vessel formation (Krivic et al., 2008)