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Also, patients should be warned about the danger of taking folic acid in place of vitamin B12, because the former may prevent anemia but allow progression of subacute combined degeneration

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For instance, one study notes that people with excess weight or obesity appear to have lower vitamin B12 levels than people who have a body mass index (BMI) in the normal range ( Additional research has observed that people who voluntarily took vitamin B12 supplements gained between 2.517 fewer pounds (1.27.7 kg) over 10 years than those who did not supplement with this vitamin ( Still, such observational studies cannot confirm whether low vitamin B12 levels are what caused the weight gain, nor whether theyre what protected against low levels

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