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Data are normalized to the NAD + abundance

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To further test the sensitivity of OSCC to chemotherapeutic drugs, the mice were intraperitoneally injected with DDP for 4 weeks (2 mg/kg, twice per week)

Toxins, diet, stress, infections, and other lifestyle factors can all cause an imbalance in the body, resulting in chronic, systemic inflammation

Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary material