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Concurrently, it induces vascular inflammation and oxidative stress, triggering endothelial cell death (including apoptosis, pyroptosis, and ferroptosis) while promoting vascular smooth muscle cell proliferation and extracellular matrix (ECM) remodeling (Lai and Kan 2015

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According to previous studies, L-carnitine positively affects spermatogenesis and sperm maturation and its metabolism (15)

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For example, Bifidobacterium animalis F1-7 can upregulate acetylcarnitine levels in the gut, thereby downregulating the TLR4/NF-B pathway and reducing lipid accumulation and inflammation in foam cells, leading to a reduction in atherosclerotic plaque accumulation [129]